Recently, researchers at the National University of Busan in Korea found that red algae extract (GAE) could inhibit high fat diet-induced obesity. Previous studies have confirmed that 12-day high intake of GAE-containing high-fat diet has a significant inhibitory effect on weight gain in mice, but no studies have shown that GAE has an effect on weight loss in obese rats.
In this study, the researchers analyzed the effects of GAE on body weight gain, fat mass, plasma, liver lipid, adipokine secretions and lipid metabolism in obese rats. The rats in the control group were divided into control group and control group. The control group consisted of five kinds of diet, all of which contained high fat.
The researchers fed a new round of diet, group 1 (high fat diet), group 2 (high fat + 0.5 g GAE), group 3 (high fat + 1 g GAE), group 4 (high fat + 2 g GAE) Group 5 (high fat + 75 g GAE). At the end of the eight-week trial, the study showed that the weight loss of the mice was the same as that of the conjugated linoleic acid (CLA) group, and CLA was a fatty acid that helped to lose weight.
The results also showed that the body weight of the GAE group was significantly lower than that of the high fat group mice. The final body weight of group 3 and group 4 was consistent with that of CLA group mice. At the same time, even if the diet of GAE content is very low, but still has a role in the control of weight.
In addition, GAE supplements can significantly reduce body weight gain, adipose tissue mass, leptin concentration, serum and liver TG, TC levels. GAE supplements can also stimulate the expression of lipid metabolism, reduce the weight of high-fat diet-induced obese mice, the future in the anti-obesity has great potential.